If you’re reading this right now then it most likely means that you’ve already passed the TMC Exam. If so, congratulations! That is an amazing accomplishment and it means that you’re one step closer to becoming a Registered Respiratory Therapist.

I just want to say thank you for coming to Respiratory Therapy Zone as a way to help prepare for the Clinical Simulations Exam. Our #1 goal is to help you pass the exam on your very first attempt. And the details that are listed out for you below in this article can set you on the right path to do just that.

We’re striving to provide you with the most current information needed to prepare for the CSE and will give you all the information that you will be expected to know for the exam by the NBRC.

So if you’re ready, let’s go ahead and dive right in!

How to pass the CSE?

First and foremost, in order to pass the Clinical Simulations Exam, it’s going to take a lot of hard work and dedication from you. There’s no way around it. This is a mindset that you must adopt early on in the preparation process.

Once you set your mind to the fact that you CAN pass the exam through hard work and dedication, it makes everything else a whole lot easier.

You need a good, reliable CSE Study Guide.

In order to learn the most important information, you need to get your hands on that information. Believe it or not, this is where many students mess up from the very beginning. And that is exactly why we created our own CSE Study Guide because we were sick and tired of seeing students fail.

Our CSE Study Guide is, without question, the best resource on the market today. But we’ll tell you more about it later on in this article.

For now, just know that it’s crucial that you are studying the right information if you want to increase your chances of passing the exam on your next attempt.

About the Clinical Simulations Exam

As I’m sure you already know, the CSE has a much different structure than the TMC Exam. Yes, the CSE shares the same topical content with the TMC. The difference is — if you only master the topical content alone, you will not get you a passing score because the CSE also tests your case-management abilities.

Our goal is to help you master both — the content and the comprehensive abilities you need to pass the exam.

Clinical Simulations Exam Rules

The test is fully computer-based, and you will have four hours to take the exam.

There will be a total of 22 problems on the exam that are selected from 8 different categories. Two of the problems are pretested scenarios that are individually scored based on the judgment of the NBRC committee.

Each problem represents a clinical setting or patient situation that is designed to simulate real-life situations in the clinical practice of respiratory care.

Keep These Rules in Mind for the Exam:

  • A pencil and a sheet of scratch paper will be provided for you. No outside notes or books are allowed. You must return your scratch paper after completing the exam.
  • No personal belongings are allowed in the testing area. You will need to leave them in your car.
  • You may leave the testing area at any time to stretch or use the restroom. Keep in mind, though, that your test timer will not stop.
  • Be on time. If you arrive more than fifteen minutes late, you will not be admitted to take the exam.
  • You will need to show two forms of identification, with at least one showing a current photograph. Both forms must be current and must include a signature.

What are the admission requirements for the Clinical Simulations Exam?

To be eligible to take the CSE, you must have obtained the CRT credential by successfully passing the TMC Exam (Therapist Multiple-Choice Examination) with the high-cut score.

This is the basic qualification for most students, although there are others that can be found on the NBRC website.

Be aware of the 3-year time limit!

You must pass the Clinical Simulations Exam within three years after graduating for a CoARC accredited Respiratory Therapy Program.

If you do not pass it within this time limit, you will be required to retake (and pass) the TMC Exam again at the high-cut score to regain eligibility.

Outside of the three-year time frame, any previous passing performance to earn the RRT credential is nullified — so please be aware of this.

How much does it cost to take the Clinical Simulations Exam?

The exam costs $200 for both new and repeat applicants. I realize that this is a significant investment, which is why it is our goal to help you pass the exam on your next attempt.

This is another reason why it’s so critical to use a CSE Study Guide that can truly prepare you for the exam. Otherwise, there’s a good chance that you’ll have to retake the exam, which means you’ll have to pay that exam fee again.

We see this far too often with students.

The good news it, if you put in the work by studying and preparing well, you can pass the exam on your first (or next) attempt, and you’ll only have to pay the fee once.

What content will be on the CSE?

As we’ve already discussed, the same content that was on the TMC Exam will be on the CSE as well. They just ask it to you in a totally different way.

Not to worry — we will cover it all inside of our CSE Study Guide. A big focus of the CSE will be on Pathology. You absolutely must how to differentiate and treat the different diseases and what to recommend for these specific patients on a case by case basis.

That is the major focus of the CSE — like it or not.

The NBRC put out a detailed content outline of exactly what to look for on the CSE. I highly recommend that you take a look over it and you can do so by visiting this link.

How are the problems structured on the CSE?

The CSE is designed to evaluate your patient management skills and ability to evaluate ongoing treatment, recommend changes, and adapt to circumstances and events.

So in order to accomplish this, they have laid out the problem in a completely different way compared to the traditional multiple-choice layout that we’re all accustomed to.

Here’s an example of how the problems will be structured on the computer screen:

Photo example by the NBRC.

As you can see, 3 windows will appear on the screen at all times during the exam.

1) There is a window with the “Scenario” at top of the screen, and your picture will be displayed in the upper right-hand corner of this window.

Each simulation begins with a brief paragraph in this window that provides preliminary information about the patient. The following sections will contain information about the changing patient situation in this window as well.

Each Scenario Window will also provide you with specific instructions about whether to “CHOOSE ONLY ONE” response in the section or to “SELECT AS MANY” responses as appropriate to gather information.

It is super-important that you follow these directions!

2) The “Options” window is displayed in the lower left portion of the screen. This window contains all options, choices, or possible responses that you can choose from.

You select an option by clicking the check box next to the option.

3) The “Simulation History” window is displayed as the lower right portion of the screen. This window shows the options chosen in the current section and the results for each choice are displayed in this window.

It also shows the “Simulation History” from all previous sections as well as the options chosen.

Basically, it helps you see the results that you selected already, in case you forgot.

When you are finished with a particular section, you can hit the “Go To Next Section” button at the bottom left of the screen to continue to the next section.

A box will pop up requesting that you confirm your wish to continue to the next section. Be sure to only click the “Yes” button when you are 100% ready to proceed to the next section, because you can’t go back.

A timer button is shown in the lower right portion of the screen and displays the time remaining for the exam. You may hide the time remaining button if you wish, simply by clicking it.

CSE Scoring

There will be a total of 22 problems on the exam that are selected from 8 different categories.

Two of the problems are pretested scenarios that are individually scored based on the judgment of the NBRC committee. The total points scored on these will be added to your results at the end.

Each version of the exam will be different which means that each version will have a minimum passing score. Of course, this is decided by the testing committee for each exam.

Exam Hint: More than half of the total possible points will come from the selections you make in the Information Gathering sections.

That is why it’s a major focus throughout this study guide.

If your final score exceeds the minimum passing score, that means you will have passed the exam.

On average, you will need to score roughly a 72% in order to pass the CSE.

That doesn’t sound so bad, right?

Now let’s talk about the actual physical points that you can get for each selection you make.

The scoring scale runs from –3 points up to 3 points. That’s right, folks. You can earn up to 3 points or you can lose up to 3 points, depending on the selections that you make.

  • Usually, there will be one best available answer that gives maximum points. (+3)
    • It is necessary for proper care and not doing it would cause harm to the patient.
  • You can earn (+2) points for selecting very important information for good patient care.
  • You can get (+1) for information that is helpful.
  • You get 0 points for the selections you make that are neither helpful nor harmful to the patient.
Now here’s where it gets dicey!
  • You lose a point (–1) for selecting something that is counterproductive.
  • You lose two points (–2) for making a selection that is very counterproductive.
  • You lose three points (–3) for making a selection that is detrimental to the patient.
    • This includes any selection that could result in harming the patient, or worse.
Obviously, it goes without saying, you want to make selections that earn you points and avoid those that take points away.

What are the components of a Clinical Simulation Problem?

There are (3) components of each CSE problem, and they are:
  1. Scenario – This establishes the setting and general parameters of the patient and (you) the Respiratory Therapist.
  2. Information Gathering – This section provides information about the patient that is normally obtained in chart review or diagnostic testing, such as vital signs, ABG results, etc.
  3. Decision Making – This is the decision point that you will need to recommend what happens next for the patient.
After being given the Scenario, you use the Information Gathering section to access the patient and make an analysis and evaluation according to the information that is provided. Then, in Decision Making, you must decide what type of therapy or response is best for the particular problem of the patient.

We will discuss each of these 3 components in more detail below.

How to Prepare for the CSE?

We’ve already touched on this earlier, but now, let’s dive a little bit deeper.

In order to increase your chances of passing the exam, you need to be prepared for the unique exam structure. As we said, the CSE covers much of the same topical content as the TMC Exam, they just ask it in a totally different way.

You have to take what you know and apply it to a real-life situation in order to make a decision to help the patient — just as if it were in a real hospital.

Exam Hint: Here’s a little “hack” that I always recommend for students. Now that you have completed the TMC Exam, you can take the results score report and use it as a guide to prioritize what you should focus on for the CSE.

Is there a section that you didn’t do so hot? You may want to dedicate some extra time looking back over that section.

By the way, these little “Exam Hint” boxes are included all throughout our CSE Study Guide. They contain some of the most important tips, tricks, and insights that all students must know in order to pass the exam.

This is one of the many perks of using our CSE Study Guide.

What diseases will be on the CSE?

Now let’s talk about all the different diseases that you must know for the exam.

As you now know, Cardiopulmonary Pathology is super-important in regard to the Clinical Simulations Exam! It’s what you should spend most of your time on when preparing for the exam.

We cover each disease in detail in our CSE Study Guide, but for now, let’s familiarize your brain with all the possible disease cases that you need to know.

Here are the 8 disease categories that you should focus on when preparing for the CSE:

Disease Category # of Cases Examples
COPD (Management) 2 Chronic Bronchitis, Emphysema, Asthma, and Bronchiectasis.

COPD (Critical Care)


2 Mechanical Ventilation and NIV management.

Adult Trauma


3 Head or Chest Injury, Pneumothorax, Burns, Drowning, Smoke Inhalation, and Hypothermia.
Cardiovascular Diseases 3 CHF, Pulmonary Edema, Heart attack, Coronary Artery Disease, and Valvular Heart Disease.
Neuromuscular Diseases 2 Guillain-Barre Syndrome, Myasthenia Gravis, Muscular Dystrophy, Stroke, and Drug overdose.

Pediatric Diseases


2 Croup, Epiglottitis, Asthma, Bronchiolitis, Foreign-body aspiration, toxic substance ingestion, and Bronchopulmonary Dysplasia.

Neonatal Diseases


2 Meconium aspiration, Apnea, Delivery Room Management, Resuscitation, RDS, and Congenital Heart Defect.
Adult Medical or Surgical 4 Head and Neck surgery, Thoracic surgery, Carbon Monoxide Poisoning, and AIDS.
Again, we cover each of these diseases in more detail inside of our CSE Study Guide, so definitely check that out if you’re interested.

But for now, let’s talk more about the structure of the exam.

What is the structure of the CSE?

Again, we already talked about this some earlier. But now, let’s dive deeper into the Scenario, Information Gathering, and Decision Making.


This will describe the physical setting for the patient and you as the Respiratory Therapist. This could include the hospital or clinic type, the home, Med-Surg unit, ICU, time or day, etc.

This is also where you will find out the general information about the patient, including their: age, sex, general appearance, and general presenting conditions.

You will also learn about the patient’s history and a brief history of the patient’s active illness or event.
Exam Hint: While reading the Scenario, the first thing you want to do is interpret if the situation is an emergency! If it is, you must take immediate action to help the patient.

If you determine that the situation is not an emergency, then you can proceed to gather more information in order to make a clinical decision.

Information Gathering

This is the section that you will be directed to in order to find out more about the patient.

They will list out 15-20 parameters for you to choose from.

For example, you will see vital signs, ABG, PFT, and various lab studies.

You must select ONLY those that are important for this patient at this particular time given what you know.

Avoid selecting anything that could be dangerous for the patient. Also, of course, avoid selecting anything that you know is unnecessary for the patient at this time.

Select only the desired information!

Once you click an option to make a selection, it will reveal that results of what you clicked on the screen.

For example, if you select that the patient needs an ABG, as soon as you click that option, it’s going to show you the patient’s ABG results on the screen.

You can then act immediately, for example, if their results were to show that they are in respiratory failure. If that were the case, what would you do?

Of course, you know this — you would want to recommend intubation and mechanical ventilation.
Exam Hint: This is important, so remember this. During the Information Gathering, if you can already tell that the situation is a medical emergency, you should act right then to help the patient.

If it’s not an emergency, you can proceed to gather more information.

Order of Progression when making your selections:

When your list of choices is available, there is a specific order that you should go through when making your selections. I’m going to share that with you now:


First and foremost, you should go through the list a select the visual things first — meaning the thing you can see.

For example, general appearance, appearance of the chest, respiratory rate, respiratory pattern, posture, sensorium, and color.

These are the things that you can literally see with your eyes. Choose all of these first. Then ask yourself, “Is there an emergency?” If not, then move on to the bedside choices.


Now you can go through the list and select the choices that can be performed at the bedside. These should all still be relatively easy to obtain.

For example, pulse, temperature, chest percussion, breath sounds, blood pressure, heart sounds, tracheal position, and capnometry, etc.

These are the things that can literally be done/checked at the patient’s bedside. After you’ve gone through the choices, is there an emergency? If no, move on to the basic lab tests.

Basic Lab Tests

Now you can select any lab tests that are necessary for this patient. Examples include ABG, CBC, 12-lead EKG, Electrolytes, and/or Chest X-ray.

These are your basic tests that still aren’t difficult to perform but are only necessary if indicated for some patients. Still no emergency? Move along to the special tests.

Special Tests

Now you can select any special test that is indicated for the patient. These are very specific and should only be selected if it’s necessary for this patient’s case.

Examples include lab tests like blood culture, PFTs, imaging studies like MRIs, CT scans, bronchoscopy, ICP, hemodynamic monitoring, and specific tests like sweat chloride test for CF, Apgar score, V/Q scan, etc.

These tests are very specific for specific patient situations.

After making all necessary selections, you should interpret the data and make proper decisions in the next section.

Exam Hint: There are a few options that you should Always select when they are available. These are quick to obtain and usually always helpful in identifying the patient’s problem.

Here are some examples: Color/general appearance, respiratory rate, heart rate, SpO2, blood pressure (if the problem deals with the heart), body temp (only if an infection is involved), level of consciousness, breath sounds, and history of present illness.

We cover this stuff in more detail inside of our CSE Study Guide.

You should only make selections if they are appropriate for the situation at hand.

For example, you probably don’t need the check any PFT results for a patient with ARDS.

Not every test should be selected for every patient. Only those that are pertinent to their situation. Are you following me here? If so, good — let’s keep moving!

Here are some general tips in regard to Information Gathering:

  • Recommend an ABG to assess the patient’s acid-base balance, oxygenation, or ventilation.
  • Assess the tracheal position to identify atelectasis or a pneumothorax. Remember that is shifts away from the affected side for a pneumothorax, and it shifts towards the affected side with atelectasis.
  • Assess percussion to identify a pneumothorax or pneumonia.
  • Select an MIP/NIF to assess the patient’s respiratory muscle strength for weaning.
  • Select Vital Capacity to check respiratory muscle strength for neurological disorders, and also for weaning.
  • Select the VE and RSBI to check for the adequacy of ventilation for weaning.
  • Assess the patient’s sputum to check for an infection.
  • Select certain PFT tests to check to see if the disease is obstructive or restrictive.
  • Again, always select blood pressure for a patient that has a cardiovascular disorder.
  • Select only certain laboratory tests that would be necessary for the patient’s specific situation. For example, you would select to assess the WBC count if the patient has an infection. That would be necessary in that situation, etc.
  • The same applies for x-rays and imaging tests. Only select them when they would help diagnose the patient. For example, a neck x-ray would be helpful to identify croup or epiglottitis or to check for a foreign body aspiration, etc.
  • Recommend to check the Intracranial Pressure for a patient with a head or brain injury.
  • If the patient is unconscious, a Glasgow Coma Scale would be necessary.
  • Never select Urinalysis. Just skip it unless you really just want to lose points. 🙂
I hope that these tips were helpful for you. These are just a few of the many tips that we share inside of our CSE Study Guide, where we go into much more detail.

Now let’s keep moving along and talk about Decision Making.

Decision Making

After you have made your selections in the Information Gathering section, you will then be directed to the Decision Making section.

This is where you must take what you know from the information given and make the best possible decision for the patient.

Usually, you will be asked to select the best of 4–5 options.

Keep in mind, sometimes you will have to make the Best Available selection if the most desired option is not listed.

Once you make the selection, it will usually say: “Physician Agrees. Done.”

Exam Hint: However, it could possibly say, “Physician Disagrees. Make another selection.”

Don’t Panic!

Just because it says this does not necessarily mean you are wrong. Proceed to pick the next best option using the information that you have available.

After you’ve made your decision, you will be taken to the next scenario. You must then evaluate how the patient responded to the decisions you previously made.

This pattern between Information Gathering and Decision Making usually cycles back and forth about 4–5 times for each problem.

You take what they give you, gather the necessary information, then make the best decision possible for the patient.

Boom, easy peasy!

I hope this simplifies things for you! It’s not as bad as people make it out to be. You just have to take it one step at a time.

Here are some general tips in regard to Decision Making:

  • Always select the ‘Best‘ option that is available to you, even though the absolute correct answer may not be listed.
  • Only select more than one choice if you’re prompted to do so.
  • Be sure to read all of the responses carefully.
  • Don’t select any unfamiliar actions. If you do not know what it means, it’s probably a bad idea to choose that one unless you can 100% rule out the other choices.
  • If the patient is wheezing, remember that there could be 3 different causes that require 3 different selections.
    • Recommend a bronchodilator for bronchospasm.
    • For wheezing with CHF, recommend diuretics.
    • A child could have wheezing caused by a foreign body aspiration — in this case, you would recommend a bronchoscopy.
  • For stridor, remember that you should recommend cool mist or racemic epinephrine.
  • If you found rhonchi or tactile fremitus while gathering information, this means that there are secretions in the large airways and the patient needs bronchial hygiene therapy or suctioning.
  • A dull percussion note means that there is consolidation — in this case, recommend lung expansion therapy.
  • Does the patient have a weak cough? Then they likely can’t cough out secretions properly. In this case, you should recommend bronchial hygiene therapy or suctioning.
  • Is the patient’s secretions yellow, green, or colored? This means that the patient likely has an infection and you should recommend antibiotics.
  • Does the patient have frothy secretions? If so, you automatically should know it’s pulmonary edema and you should recommend BiPAP or NPPV for this patient.
  • ABG interpretation is also important! You passed the TMC Exam, so I know you already know how to do so. Here are things to keep in mind when interpreting ABGs for the CSE:
    • A really low pH with a high CO2 and normal HCO3 means acute ventilatory failure. Recommend mechanical ventilation.
    • A normal pH with high CO2 and high HCO3 means chronic ventilatory failure. Recommend low-flow oxygen and avoid intubation if possible.
    • A high pH with a normal CO2 and a high HCO3 means acute metabolic alkalosis. Recommend either potassium or chloride, depending on what is needed.
    • A low pH with a normal CO2 and a low HCO3 means acute metabolic acidosis. You should increase the ventilation and treat the underlying cause.
  • If the patient has a PaO2 > 60 on an FiO2 < 60%, this is moderate hypoxemia (V/Q imbalance). You should recommend oxygen therapy and treat the underlying problem.
  • If the patient has a PaO2 < 60 on an FiO2 > 60%, this is severe hypoxemia (shunting). You should recommend oxygen therapy with PEEP/CPAP and treat the underlying cause.
Again, these are just a few of the basic things I want you to remember to get the juices flowing in your brain.

For more tips and insights, check out our CSE Study Guide.

Final Thoughts

So there you have it! That wraps up our guide on how to prepare for (and pass) the clinical simulations exam. I truly hope that this information was helpful for you.

This wasn’t meant to teach you everything you need to know in order to pass the CSE. We couldn’t possibly fit everything into one article.

However, this information will definitely set you on the right path to learning exactly what you need to know so that you can earn your RRT credential.

If you enjoyed what you just read, then you’ll definitely get even more out of our CSE Study Guide. We created it to specifically help students pass the CSE on their very next attempt. 

Our CSE Study Guide is only for those who are serious about passing the exam on their very next attempt. If that’s you, click the button below to learn more.

We’re very fortunate to help so many Respiratory Therapy Students around the world and it brings me great joy that our study guide is already helping students pass the exam.

So if you’re ready to pass the CSE on your next attempt as well, Click Here to Learn More.

Thanks again for reading and I wish you the best of luck. And as always, breathe easy my friend.