Bronchiectasis Overview and Practice Questions Vector

Bronchiectasis: Overview and Practice Questions (2024)

by | Updated: Mar 18, 2024

Bronchiectasis is a chronic respiratory condition characterized by the abnormal widening and scarring of the airways in the lungs.

This condition, often a result of recurring lung infections, can lead to a range of debilitating symptoms, including persistent coughing, excess mucus production, and difficulty breathing.

While it may not be as widely recognized as some other respiratory diseases, bronchiectasis significantly impacts the lives of those affected by it.

In this article, we will delve into the key aspects of bronchiectasis, from its causes and symptoms to its management and the importance of early diagnosis.

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What is Bronchiectasis?

Bronchiectasis is a chronic lung condition characterized by irreversible widening and damage to the bronchial tubes, the airways that carry air to the lungs. This damage impairs the ability to clear mucus and leads to persistent coughing, difficulty breathing, and recurrent lung infections.

Bronchiectasis Mucus Lungs Vector Illustration


Bronchiectasis can be caused by a variety of factors, including:

  • Infections: Recurrent or severe respiratory infections, such as pneumonia or tuberculosis, can damage the bronchial tubes and lead to bronchiectasis.
  • Autoimmune diseases: Conditions like rheumatoid arthritis or inflammatory bowel disease can cause inflammation in the airways, contributing to bronchiectasis.
  • Genetic factors: Some individuals may inherit genetic mutations that make them more susceptible to bronchiectasis.
  • Allergies: Severe allergies can lead to chronic inflammation in the airways, increasing the risk of bronchiectasis.
  • Inhalation of irritants: Exposure to irritants like toxic fumes or dust over an extended period can contribute to the development of bronchiectasis.
  • Gastroesophageal reflux disease (GERD): Stomach acid can enter the airways and cause irritation, potentially leading to bronchiectasis.
  • Cystic fibrosis: This genetic disorder can result in thick, sticky mucus that can block airways and lead to bronchiectasis.
  • Immunodeficiency disorders: Conditions that weaken the immune system can make individuals more susceptible to lung infections and bronchiectasis.

Note: It’s important to identify and address the underlying cause of bronchiectasis to manage the condition effectively and prevent further damage to the airways.

Signs and Symptoms

The signs and symptoms of bronchiectasis can vary in severity but typically include:

  • Persistent cough: A chronic cough is a common early symptom, often producing mucus or sputum.
  • Excessive mucus production Individuals with bronchiectasis often have increased mucus in their airways, which can be thick and difficult to clear.
  • Shortness of breath: Difficulty breathing, especially during physical activity, is a frequent symptom.
  • Recurrent respiratory infections: Frequent lung infections, such as bronchitis or pneumonia, can occur.
  • Chest pain or discomfort: Some people may experience chest pain or tightness.
  • Fatigue: Chronic coughing and breathing difficulties can lead to fatigue.
  • Wheezing: Wheezing sounds during breathing may occur in some cases.
  • Clubbing of fingers: In advanced cases, the fingertips may appear enlarged and rounded.

Note: Symptoms can worsen over time, and it’s essential for individuals experiencing these signs to seek medical evaluation and treatment. Early diagnosis and management can help improve quality of life and slow the progression of the condition.


Diagnosing bronchiectasis typically involves a combination of medical history assessment, physical examination, and diagnostic tests.

The following steps are commonly used to diagnose the condition:

  • Medical history and physical examination: This involves performing a patient assessment, reviewing their signs and symptoms, medical history, and any risk factors for bronchiectasis.
  • Chest imaging: Imaging tests are crucial for confirming the diagnosis. High-resolution computed tomography (HRCT) scans of the chest provide detailed images of the bronchial tubes and can reveal bronchiectasis, its extent, and the pattern of damage.
  • Sputum culture: Collecting a sample of sputum (mucus coughed up from the lungs) can help identify the presence of bacteria, which is important for guiding antibiotic treatment.
  • Pulmonary function tests: These tests measure lung function and can help assess how well the lungs are working. They may include spirometry and lung volume tests.
  • Blood tests: Blood tests can help rule out other conditions and assess for underlying causes, such as autoimmune disorders or immunodeficiency.
  • Bronchoscopy: In some cases, a bronchoscopy may be performed, where a thin, flexible tube with a camera is inserted into the airways to directly visualize and assess any abnormalities.

Note: Once diagnosed, the underlying cause of bronchiectasis should be determined if possible, as treatment may vary depending on the cause.


The treatment of bronchiectasis focuses on managing symptoms, preventing complications, and addressing the underlying cause when possible.

Treatment options may include:

  • Antibiotics: Antibiotics are often prescribed to treat and prevent lung infections, which are common in people with bronchiectasis. The choice of antibiotic and duration of treatment depend on the specific infection and its severity.
  • Bronchodilators: These medications help relax and open the airways, making it easier to breathe. They can alleviate symptoms like coughing and shortness of breath.
  • Airway clearance therapy: Physical techniques, such as postural drainage, chest percussion, and deep breathing exercises, can help loosen and clear mucus from the airways.
  • Mucolytic agents: Medications like dornase alfa can help thin and improve the clearance of thick mucus in the airways.
  • Respiratory therapy: The patient may require oxygen therapy to treat or prevent hypoxemia. Noninvasive ventilation (NIV) may be indicated to treat an acute exacerbation, and, in severe cases, intubation and mechanical ventilation to prevent respiratory failure.
  • Vaccinations: Keeping up-to-date with vaccinations, including the annual flu and pneumonia vaccines, can help reduce the risk of respiratory infections.
  • Pulmonary rehabilitation: This program may include exercise training, education, and support to improve lung function and overall well-being.
  • Lifestyle modifications: Avoiding smoking, managing allergies, and maintaining good overall health through a balanced diet and regular exercise are essential for managing bronchiectasis.
  • Treating underlying causes: If an underlying condition, such as gastroesophageal reflux disease (GERD) or autoimmune disorders, contributes to bronchiectasis, it should be treated or managed accordingly.

In severe cases, when conservative measures are insufficient, some individuals may be considered for surgical options, such as lung resection or lung transplantation.

It’s crucial for individuals with bronchiectasis to work closely with their healthcare providers to develop a personalized treatment plan tailored to their specific needs and circumstances.

Regular monitoring and ongoing care are essential to manage the condition effectively and improve quality of life.

Bronchiectasis Practice Questions

1. What is the definition of bronchiectasis?
Bronchiectasis is a chronic lung condition characterized by irreversible widening and damage to the bronchial tubes, leading to persistent coughing, difficulty breathing, and recurrent lung infections.

2. What are the causes of the bronchiectasis?
Bronchiectasis can be caused by various factors, including respiratory infections, autoimmune diseases, genetic mutations, exposure to irritants, severe allergies, and certain underlying conditions, leading to the irreversible widening and damage of the bronchial tubes in the lungs.

3. What is the pathophysiology of bronchiectasis?
The pathophysiology of bronchiectasis involves the permanent dilation and damage of the bronchial tubes due to chronic inflammation and infection, leading to impaired mucociliary clearance and recurrent respiratory infections.

4. What are the shapes of the destroyed bronchial walls?
Varicose, fusiform, saccular, cystic, and cylindrical.

5. Is there a cure for bronchiectasis?
There is no cure for this disease; however, teatment and management of the symptoms are very important.

6. What are some signs, symptoms, and observations of bronchiectasis?
It often causes a continuous cough with a large amount of sputum, recurrent local pneumonia, occasional hemoptysis, and increasing dyspnea.

7. What breath sounds are associated with a severe state of bronchiectasis?
Rales and rhonchi

8. What is the old method of diagnosing bronchiectasis?

9. What is the latest method used to diagnose bronchiectasis?
CT scan and HRCT

10. What happens in the lungs of patients suffering from bronchiectasis?
Bronchial walls are destroyed, mucosal atrophy, cilia are destroyed, elastic area is filled with pus, and the distal areas become obstructed.

11. What are some problems associated with bronchiectasis?
Digital clubbing, atelectasis, consolidation, increased thickness of the A-C membrane, bronchospasm, and excessive bronchial secretions.

12. What does the pulmonary function test of a patient with bronchiectasis typically show?
Obstructive patterns

13. What does the ABG show in a patient with mild to moderate bronchiectasis?
Respiratory alkalosis with hypoxemia

14. What does the ABG show in a patient with severe bronchiectasis?
Compensated respiratory acidosis with hypoxemia

15. What are some common infections associated with bronchiectasis?
Haemophilus influenzae, streptococcus, staphylococcus, pneumonia, moraxella catarrhalis, and pseudomonas in cystic fibrosis patients.

16. Why is airway clearance important in the treatment and management of bronchiectasis?
Airway clearance improves the patient’s ability to breathe and decreases the risk of infections.

17. What is the prognosis of bronchiectasis?
The prognosis is extremely variable and depends on the extent of the damage. Good management is very important.

18. What are the ABG results for patients with bronchiectasis?
For mild to moderate cases, it shows acute alveolar hyperventilation with hypoxemia. In severe cases, the results will show chronic ventilatory failure with hypoxemia.

19. What ethnicity is bronchiectasis more common in?
Bronchiectasis is more common in Asians and Pacific Islanders and less common in African Americans.

20. What age is bronchiectasis more common in older patients?
Bronchiectasis is more common among people 50-70 years old.

21. Is bronchiectasis more common in men or women?
Bronchiectasis is more common in women.

22. What is the etiology of bronchiectasis?
50% of bronchiectasis cases are idiopathic, 25% occurs from a post-infection condition, and 15% is caused by systemic diseases. Many people with cystic fibrosis end up with bronchiectasis, but this is a small portion of the total population. 

23. What lung condition is bronchiectasis often misdiagnosed as?

24. How do you diagnose bronchiectasis?
CT scan and a history of a chronic cough with sputum.

25. How does cystic fibrosis cause bronchiectasis?
Cystic fibrosis causes bronchiectasis by producing thick, sticky mucus that obstructs the airways, leading to chronic infections, inflammation, and eventually, the dilation and scarring of the bronchial walls.

26. What are the laboratory results of hemoglobin and hematocrit in patients with bronchiectasis?
The results will show increased values.

27. How do you treat chronic bronchiectasis with pseudomonas?

28. What will a CT scan look like for a patient with post-tuberculosis bronchiectasis?
The lower left lung will show evidence of local damage. 

29. What is a primary ciliary dyskinesia?
Primary ciliary dyskinesia is a hereditary condition characterized by defective ciliary structure and function, leading to impaired mucociliary clearance and resulting in chronic respiratory tract infections and associated complications.

30. What are the complications of primary ciliary dyskinesia?
Neonatal respiratory distress, daily wet cough from birth, chronic airway disease with age-dependent bronchiectasis, recurrent otitis media, and reduced fertility.

31. What are the clinical symptoms associated with bronchiectasis?
The symptoms include neonatal respiratory problems, recurrent otitis media, recurrent sinusitis, recurrent pancreatitis, gastrointestinal disease, infertility in men, and finger clubbing. In addition, patients will have recurring coughs with lots of infected sputum, intermittent hemoptysis, persistent halitosis or bad breath, dyspnea, and recurrent febrile episodes.

32. What are macrolides in treating bronchiectasis?
Macrolides are helpful in bronchiectasis because they are both anti-inflammatory and anti-microbial. Macrolides reduce bronchiectasis exacerbations, improve quality of life, and decrease inflammation.

33. When do you use IV antibiotics to treat bronchiectasis?
IV antibiotics are used during a bronchiectasis exacerbation where symptoms worsen and an infection is present.

34. What will spirometry results show in patients with bronchiectasis?
Decreased flow rates

35. What will the CBC results show in patients with bronchiectasis?
Increased RBC/Hb/Hct

36. What observation is seen in the sputum of patients with bronchiectasis?
It may indicate that an infection is present.

37. What does chronic dilation of the airways lead to?
It leads to chronic infections and inflammation.

38. What is the difference between COPD and bronchiectasis?
COPD is a progressive disease that causes airflow obstruction due to alveolar damage, while bronchiectasis specifically involves the abnormal widening of airways due to chronic infection and inflammation, not necessarily accompanied by the alveolar damage seen in COPD.

39. What are the five primary causes of bronchiectasis?
Idiopathic, congenital, post-infectious, immunodeficiency, and other causes.

40. What percentage of bronchiectasis is a result of idiopathic causes?

41. What are four congenital causes of bronchiectasis?
Cystic fibrosis, primary ciliary dyskinesia, Kartagener’s syndrome, and Young’s syndrome.

42. What are five post-infectious causes of bronchiectasis?
Measles, pertussis, pneumonia, tuberculosis, and bronchiolitis.

43. What type of immunodeficiency is associated with bronchiectasis?

44. What is the typical history of a patient who presents with bronchiectasis?
Usually, there is a history of a chronic productive cough and recurrent chest infections.

45. What are the main symptoms associated with bronchiectasis?
Persistent cough with purulent sputum, hemoptysis, fever, weight loss, digital clubbing, coarse inspiratory crepitations, and wheezes.

46. What are the potential complications of bronchiectasis?
Pneumonia, pleural effusion, pneumothorax, pulmonary hypertension, massive hemoptysis, cerebral abscess, and amyloidosis.

47. What tests are performed in patients with suspected bronchiectasis?
Sputum, blood, spirometry, chest x-ray, high-resolution CT of the chest, bronchoscopy, and a sweat test for cystic fibrosis.

48. What specific blood tests are ordered for patients with bronchiectasis?
Serum immunoglobulin, aspergillus precipitins test, rheumatoid factor, α1-antitrypsin level, and assessment of Ig response to pneumococcal vaccine.

49. What pattern with spirometry show in a patient with bronchiectasis?
Obstructive patterns

50. What signs would you expect on the chest x-ray of a patient with bronchiectasis?
Dilated bronchi with thickened walls and multiple cysts containing fluid.

51. What test is the gold standard for diagnosing bronchiectasis?
HRCT of the chest

52. Why would you conduct a bronchoscopy in patients with suspected bronchiectasis?
To locate the site of hemoptysis, exclude obstruction, and obtain samples for culture.

53. What anatomic alterations are included in patients with bronchiectasis?
Hyperinflation and consolidation

54. What is a congenital cause of bronchiectasis?
Cystic fibrosis

55. What condition can occur in children if parents don’t give the usual childhood immunizations and the child has been repeatedly hospitalized with pulmonary infections?

56. What should be done to prevent bronchiectasis from worsening?
Avoid air pollution, get an influenza vaccination, and avoid smoking.

57. What other conditions are associated with severe bronchiectasis?
Cor pulmonale, distended neck veins, and polycythemia.

58. What will the hematology test results show in patients with bronchiectasis?
It will show an elevated WBC count with increased hemoglobin and hematocrit.

59. What are the hallmark symptoms of bronchiectasis?
Chronic cough with production of large quantities of foul-smelling sputum.

60. What is the usual characteristic of the sputum of patients with bronchiectasis?
It is usually voluminous and tends to settle into several different layers.

61. What signs do patients with severe bronchiectasis have?
Distended neck veins, pitting edema, and an enlarged and tender liver.

62. What lobe of the lung is bronchiectasis frequently found in?
The lower lobes

63. What part of the airway does bronchiectasis usually affect?
Smaller bronchi

64. What are the three forms of bronchiectasis?
Varicose, cylindrical, and cystic

65. What form of bronchiectasis has irregular dilations and constrictions and appears distorted and bulbous?

66. What is the other name for varicose bronchiectasis?

67. What form of bronchiectasis has a tube-like dilation, where they lose their natural taper for 6-20 generations and appear to end squarely?

68. What is the other name for cylindrical bronchiectasis?

69. What is the other name for cystic bronchiectasis?

70. What are two types of bronchiectasis?
Acquired and congenital

71. What are the two types of acquired bronchiectasis?
Pulmonary infection and bronchial obstruction

72. What kind of congenital bronchiectasis causes problems with mucus clearance and thick, stagnant secretions that leads to obstruction and frequent infections?
Cystic fibrosis

73. What happens to the fingers due to chronic hypoxemia?
Digital clubbing

74. What are the potential types of bacteria in bronchiectasis sputum?
Haemophilus influenzae, pseudomonas aeruginosa, and anaerobic organisms.

75. What type of disease is bronchiectasis?
Obstructive lung disease

76. What type of ventilatory acid-base assessment does a mild to moderate bronchiectasis have?
Acute alveolar hyperventilation with hypoxemia

77. What type of ventilatory acid-base assessment does a severe bronchiectasis have?
Chronic ventilatory failure with hypoxemia

78. What is performed by injecting an opaque contrast material into the airway to show the extent of the bronchiectasis disease?
Bronchogram, although this method is no longer used.

79. What type of bronchiectasis has increased opacity due to tissue density?

80. What type of bronchiectasis has translucent lung fields?

Final Thoughts

Bronchiectasis is a chronic pulmonary disorder that presents unique challenges for both patients and healthcare providers.

Understanding its underlying causes, recognizing its symptoms, and obtaining an accurate diagnosis are crucial steps in managing this condition effectively.

While there is no cure for bronchiectasis, a comprehensive treatment approach, including airway clearance techniques, antibiotics, and lifestyle adjustments, can help individuals with bronchiectasis lead more comfortable and fulfilling lives.

John Landry, BS, RRT

Written by:

John Landry, BS, RRT

John Landry is a registered respiratory therapist from Memphis, TN, and has a bachelor's degree in kinesiology. He enjoys using evidence-based research to help others breathe easier and live a healthier life.


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  • Rrt, Des Terry Jardins MEd, and Burton George Md Facp Fccp Faarc. Clinical Manifestations and Assessment of Respiratory Disease. 8th ed., Mosby, 2019.
  • Bird K, Memon J. Bronchiectasis. [Updated 2023 May 22]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023.

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